What type of bacteria is KPC?

Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria are a group of emerging highly drug-resistant Gram-negative bacilli causing infections associated with significant morbidity and mortality.

How is KPC production detected?

For the recognition of KPCs, have been established several phenotypic tests (12, 25). The method presently approve by the CLSI is the modified Hodge test (MHT) and this method is accepted as a specific and sensitive method for detection of carbapenemase (26, 27).

How is Klebsiella pneumoniae diagnosed?

Conventional methods used to detect K. pneumoniae based on the phenotypic system include microscopic examination, biochemical identification, and the use of newly developed automatic bacterial identification instruments, such as the VITEK®2 system (Hay et al., 2007).

What is carbapenem-resistant Klebsiella pneumoniae?

Carbapenem-resistant Klebsiella pneumoniae (CRKP) is one of the carbapenem-resistant Enterobacteriaceae (CRE), an emerging cause of antibiotic-resistant, health care-associated infections. CRE were listed as one of the most urgent antibiotic resistance threats by the CDC and WHO (4, 5).

What antibiotics is KPC resistant to?

When aminoglycoside susceptibility is identified, aminoglycosides are an important therapeutic option for the treatment of KPC-producing bacteria. However, pan-resistant bacteria have been reported that are resistant to tigecycline, polymixin, and aminoglycosides.

What are the symptoms of KPC?

Klebsiella pneumoniae symptoms

• fever.
• chills.
• coughing.
• yellow or bloody mucus.
• shortness of breath.
• chest pain.

Is KPC a gene in bacteria?

KPCs are encoded by the gene blaKPC, whose potential for inter-species and geographic dissemination is largely explained by its location within a Tn3-type transposon, Tn4401. This transposon is a genetic element which is capable of inserting into diverse plasmids of Gram-negative bacteria.

What does KPC mean?

KPC means “Keep Parents Clueless.” The abbreviation KPC is commonly used during text or chat conversations between children or teenagers who are undertaking or planning an activity (online or offline) that they wish to keep secret from adults.

Can Klebsiella pneumoniae be cured?

Klebsiella infections that are not drug-resistant can be treated with antibiotics. Infections caused by KPC-producing bacteria can be difficult to treat because fewer antibiotics are effective against them. In such cases, a microbiology laboratory must run tests to determine which antibiotics will treat the infection.

How did I get Klebsiella in my urine?

Klebsiella UTIs occur when the bacteria enters the urinary tract. It can also happen after using a urinary catheter for a long time. Typically, K. pneumoniae cause UTIs in older women.

What diseases does Klebsiella pneumoniae cause?

Klebsiella [kleb−see−ell−uh] is a type of Gram-negative bacteria that can cause different types of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis.